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(Database last updated on Mar 27, 2024)
| ID Number | 933 | |
| Study Type | In Vivo | |
| Model | 2450 MHz (CW) exposure to mice and analysis of avoidance behavior | |
| Details | CF1 mice were exposed to 2450 MHz (CW) MW at SARs of up to 60 W/kg, sufficient to elevate core body temperature, as mice were held at ambient temperatures between 20 to 35°C. Exposure was performed using a waveguide exposure system described previously (Ho et al., IEEE Trans Microwave Theory Tech (1973) 21:837-840). The authors report that at high SAR, mice orient and posture themselves with respect to the field to reduce energy and heat absorption. At higher ambient temperature, it took less exposure to elicit this behavior. In a subsequent study, mice trained to perform an operant behavior (interrupting a light beam) to avoid exposure to 2450 MHz (CW) MW as above at 46 W/kg were given the psychoactive drugs chlordiazepoxide, chlorpromazine hydrochloride, or d-amphetamine sulfate 15 minutes prior to the exposure sessions. Chlordiazepoxide decreased the animals avoidance responding and resulted in an increase in exposure periods. The data with the other two drugs was highly variable and no correlations could be drawn. |
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| Findings | Effects (only at thermal levels) | |
| Status | Completed With Publication | |
| Principal Investigator | FDA, Washington DC, USA | |
| Funding Agency | DOH, UK, FDA, USA | |
| Country | UNITED STATES | |
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