ID Number		882
Study Type		In Vivo
Model		Ultrasound (CW) exposure to large animal brains and analysis of tissue damage and cell death
Details		Animals were heated with ultrasound (CW) exposure as well as non-RF heating. Elevation of brain temperature from ~43 degrees to 70 degrees resulted in damage to the white and gray matter, with the time required for damage proportional to the temperature of the tissue in a dose dependent fashion. Elevation of brain temperature even to 42 degrees for 8 hours did not cause obvious gross pathological damage to the brain, although it was sufficient to cause damage fetal damage in pregnant dams. The study showed no difference between heating with ultrasound, laser, conventional heat with damage always dependent on absolute temperature.
Findings		Effects (only at thermal levels)
Status		Completed With Publication
Principal Investigator
Funding Agency		Private/Instit.
Country		UNITED STATES
References		Lele, PP Ultrasound Med Biol., (1979) 5:307-320
Comments