ID Number		88
Study Type		In Vivo
Model		936, 950 MHz (GSM) exposure to rats and analysis of hearing
Details		Sprague Dawley rats were exposed at average SARs in the head of 0.2 W/kg (936 MHz) for 3 h/d for 3 days or 1.0 W/kg (950 MHz) for 3 h/d for 5 days. Exposure was performed on rats restrained in a carrousel array with four loop antennas resulting in simultaneous exposure of 12 rats. No effect of exposure was found on otoacoustic emissions from the cochlea which were measured as an indicator of outer hair cell subclinical or clinical pathology. No effect of exposure on Distortion Product Otoacoustic Emissions (DPOAE) or on cochlea tissue was observed by histopathological analysis after 1 week exposure using 1 W/kg. Functional analysis at 0, 2, 48, and 72 hr after 1 week exposure using 1 W/kg also showed no effects. Additional studies exposing rats to 900 MHz at SARs betweem 4.4 +/- 1.2 W/kg (experimentally determined) to 5.5 +/- 1.1 W/kg (numerically determined) for 2 weeks did not result in any effects on DPOAE. A follow-on study exposed rats (n = 48) to either 900 or 1800 MHz (GSM) at 2 W/kg (head average) for 2 hours/day, 5 days/week, for 4 weeks using a similar exposure setup. Again, the authors reported no effect of exposures on DPOAE, either in amplitude or signal-to-noise ratio. The authors did report that the first week of exposure showed the most variation in signal-to-noise, likely a result of stress due to the restraint. In a recent 2007 report, rats exposed to 900 MHz (GSM) 2 hrs/day, 5 days/week, 4 weeks to 4 W/kg were analyzed using otoacoustic emission testing with or without Gentimicin. No effects of RF were observed.
Findings		No Effects
Status		Completed With Publication
Principal Investigator		Dept of Environment / ENEA, Italy - marino@casaccia.enea.it
Funding Agency		EU, Elettra 2000, Italy, Agency Tech, Energy, Environ, Italy, GUARD, EU 5th Framework, Europe
Country		ITALY
References		Parazzini, M et al. Radiation Research, (2007) 167:600-605 Galloni, P et al. Radiation Research, (2005) 164:798-804 Galloni, P et al. Bioelectromagnetics, (2005) 26 (Suppl 7):536-547 Marino, C et al. Radiat. Environ. Biophys., (2000) 39:131-136
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