ID Number		86
Study Type		In Vivo
Model		900, 1800 MHz (CW, GSM) exposure to mice and analysis of behavior and brain activity.
Details		C57BL/6J (male) mice were exposed to 900 MHz and/or 1800 MHz GSM signals in a plexiglass rocket waveguide system for 45 minutes/day for 10 days at 0.5 W/kg (whole body average) and tested in an appetite motivated 8-arm radial maze for effects on spatial learning and memory. Mice used to test behavior were trained 4 days on the Morris water maze prior to exposure and analyzed following exposure for latency to escape, swim pattern, and swimming speed. Tests were performed immediately after exposure, or following a 15 or 30 minute recovery period. Mice used for analysis of gene expression and electrophysiological responses from prepared hippocampal slices were sacrificed immediately following exposure. All studies were performed in a blinded fashion. No significant effects were observed as a result of RF exposure. Follow-up studies were also unable to replicate Lai (1994) results reporting RF exposure having an effect on transient stress or performance in a water maze.
Findings		No Effects
Status		Completed With Publication
Principal Investigator		NRPB, UK - richard.saunders@nrpb.org.uk
Funding Agency		HPA (NRPB), UK
Country		UNITED KINGDOM
References		Sienkiewicz, ZJ et al. Bioelectromagnetics, (2000) 21:151-158 Sienkiewicz, Z et al. International Journal of Environmental Research and Public Health., (2019) 16:1607- Broom, KA et al. Bioelectromagnetics., (2019) 40:498-511
Comments		5 studies [Sienkiewicz et al (2005), Sienkiewicz et al (2000), Dubreuil et al., Cobb et al., and Cassel et al] now unable to confirm Lai et al (1994) initial report.