ID Number		824
Study Type		In Vivo
Model		1.25 GHz (PW) exposure to rats and analysis of brain pathology
Details		Sprague Dawley rats were exposed to 1.25 GHz (PW-6 usecond pulses at 10 Hz) at 0,0.6, or 6 W/kg (whole body SAR) for 30 minutes. In some cases, exposure followed an initial intraperitoneal injection of 10 mg/kg 3-NP (3-nitropropionic acid causing chemical hypoxia). Analysis of caudate putamen neurons was reported to show increasing qualitative abnormalities in a dose dependent manner in the absense of 3-NP, but not with 3-NP injection. In addition, without 3-NP the nuclear envelop and rough endoplasmic reticulum (RER) dimensions at 6 W/kg were increased 2 fold over controls and 0.6 W/kg groups. 3-NP injection added to the RF effect on RER. The authors speculate that the effects may have been caused by thermal stress or energy deplition.
Findings		Effects
Status		Completed With Publication
Principal Investigator		Brooks AFB, USA - ronald.seaman@brooks.af.mil
Funding Agency		AF, USA
Country		UNITED STATES
References		Seaman, RL et al. Bioelectromagnetics, (2005) 26:82-101
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