ID Number		799
Study Type		In Vivo
Model		2450 MHz (CW and PW) exposure to young rats and analysis of brain chemistry
Details		Albino rats (7 days old) were exposed to 2450 MHz (CW or PW at 100 pulses/sec, 2 usec pulse width, 2.5 KW peak power) at an average field intensity of 8.26 mW/cm2 for 28 days (24 hours per day) and analyzed for changes in AMP, ADP, and ATP levels in the brain. Exposure to both CW and PW 2450 MHz MW resulted in a reported decrease in ADP levels in the brain. Exposure to CW (but not PW) 2450 MHz MW also resulted in a reported increase in AMP levels. Preliminary studies of exposure in prenatal and postnatal rats from this same lab had also demonstrated changes in brain AMP, ADP, and ATP levels.
Findings		Effects
Status		Completed With Publication
Principal Investigator		University of Sarajevo, Yugoslavia
Funding Agency		FDA, USA
Country		UNITED STATES
References		Jamakosmanovich, A et al. Period. Biol., (1983) 85:199-201 Shore, ML et al. SYMPOSIUM ON BIOLOGICAL EFFECTS AND MEASUREMENT OF RADIO FREQUENCY/MICROWAVES. D.G. Hazzard, editor. HEW Publication (FDA) 77-8026., (1977) :280-289
Comments		There was a lack of temperature monitoring, positive controls, and exposure system characterization. While incident field values were provided, no information on SAR levels was determined (either from calculation or experimentally). The results may have been confounded by a number of variables, and experimental procedures were not describe in enough detail to critical analysis or replication. The results were further not consistent from a mechanistic standpoint.