ID Number		797
Study Type		In Vitro
Model		53.6, 61.2, 78.2 GHz exposure to liposomes and bacteria and analysis of membrane oxidative damage
Details		Liposomes (phosphatidyl choline) were exposed to 53.6, 61.2, and 78.2 GHz mm waves at (peak) SARs of 800, 84, and 8000 W/kg, respectively, for either 30 or 60 minutes and analyzed for effects on lipid peroxidation. Exposure was reported to result in a significant (>5 degree, from 25 to >30 degrees C) increase in temperature of the in vitro system. UV light exposure at 302 nm was used as a positive control. Mm wave exposure had no effect on peroxidation product formation, even in the presence of ADP-Fe+++ or EDTA-Fe+++. Further, mm wave exposure in the presence of melanin did not result in increased formation of superoxide or hydrogen peroxide by-products. The authors conclude that mm wave exposure to liposomes at the above field intensities does not result in increased peroxidation.
Findings		No Effects
Status		Completed With Publication
Principal Investigator		Temple University, Philadelphia PA, USA
Funding Agency		Private/Instit.
Country		UNITED STATES
References		Logani, MK et al. Radiat. Res., (1996) 145:231-235 Rojavin, MA et al. Bioelectromagnetics, (1995) 16:188-196 Philippova, TM et al. Bioelectromagnetics, (1994) 15:183-192
Comments		The temperature was not monitored or regulated properly and increased markedly during exposure. Although the system probably did have significant elevated temperature gradients and hot spots, since no effect was reported this did not result in any false positive findings. The use of UV light as a positive control was appropriate, but a non-MW heat control might have also been informative.