ID Number		675
Study Type		In Vivo
Model		2450 MHz (CW) exposure to pregnant monkeys and analysis of behavioral responses in offspring
Details		Squirrel monkeys were exposed to 2450 MHz (CW) MW for 3 hours/day, 5 days/week at 0.034, 0.34, or 3.4 W/kg (whole body average). Exposures were performed on pregnant female adults during the third trimester of pregnancy. In addition, some of the offspring groups were also exposed through 6 months of age. No effects of either exposure schedule were observed on live births, deaths, body mass, perceptual motor development of pups, home cage observations of mothers and pups, urinary catecholamines (epinephrine and norepinephrine), blood cortisol, blood lymphocyte DNA and RNA biosynthesis, or EEG (both baseline and photic driven EEGs). While an initial finding of higher mortality rate in young monkeys (pre-weaning) exposed at the highest exposure level both before and 6 months after birth was observed, this was not replicated in a larger follow-up study (see note added in proof in Radio Science (1982) 17:135s-144s).
Findings		No Effects (even at thermal levels)
Status		Completed With Publication
Principal Investigator		EPA, USA
Funding Agency		EPA, USA
Country		UNITED STATES
References		Kaplan, J et al. Radio Sci., (1982) 17:135-144
Comments		The study also reportedly showed no behavioral signs of being overheated, the lack of core temperature measurements during exposure makes it impossible to determine whether thermal stress played a role in the observed mortality increase. However, the lack of confirmation in the follow-up study makes this more of a mute point. There was also no positive or heat control in monkeys (probably for cost reasons), although the authors did try to extrapolate information from thermally stressed rats.