ID Number		669
Study Type		In Vivo
Model		2450 MHz (CW) exposure to mice and analysis of immune parameters and digestive function
Details		BALB/c mice were exposed to 2450 MHz (CW) MW for 4 hr/day, 4 days at SARs of 5-14 W/kg in an anechoic chamber. Exposure at 20 mW/cm2 decreased cell-mediated cytotoxicity and increased NK activity. Exposure also stimulated antibody production by the SRBC plaque forming assay and significantly increased survival in animals inoculated with K. pneumonia. The authors suggest these effects may be the result of interactions on multiple blood cell types. In a related study, Wistar rats were exposed to 2450 MHz (CW) MW at SARs of 4-7 W/kg for 4-8 hr. Exposure for 8 hrs accelerated digestive transit for up to 24 hrs after exposure. When electrodes were implanted in the duodenal wall slow-wave frequencies were accelerated and action potentials were inhibited. The authors conclude that while the acceleration of slow waves may be a thermal effect, the inhibition of action potentials has to be considered as a non-thermal MW effect.
Findings		Effects
Status		Completed With Publication
Principal Investigator		Lab Physiology & Pharmacodynamics, INSA, France - rsantini@insa.insa-lyon.fr
Funding Agency		Private/Instit.
Country		FRANCE
References		Deschaux, P et al. J. Microwave Power, (1984) 19:107-110 Santini, R J. Microwave Power, (1982) 17:329-334
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