ID Number		603
Study Type		In Vivo
Model		915, 2450 MHz (CW) exposure to rats and analysis of behavioral performance
Details		Long-Evans rats were exposed to 2450 MHz CW microwaves at an SAR of 0.14 W/kg (whole body, range of 0.11-0.18 W/kg) for 7 hr/day, 7 days/wk, for 90 days in an anechoic chamber. No effect of microwave exposure was observed for footshock reactivity or in open field tests. Some statistically significant but variable results were observed in a two-way active avoidance shuttlebox task and in a schedule-controlled lever-press response for food pellets. No effect of microwaves on urine 17-ketosteroid, red blood cell, plasma cholinesterase, or total plasma sulfhydryl group levels was observed. In a similar study, rats were exposed as above, but at SARs of 0.70 W/kg (whole body average). In this study, differences between exposed and sham-control rats were observed for open-field tests in addition to the shuttlebox avoidance and lever-pressing for food pellet tests. In an earlier study, Long-Evans rats were exposed to 915 MHz (CW) MW for 8 hr/day, 5 days/wk, for 16 weeks at an SAR of 2.46 W/kg. Although a difference in circulating blood sulfhydryls was noted, no effects were observed on activity, tissue histology, EEG, or a number of other hematopoietic factors (RBC, WBC, neutrophil, lymphocyte counts, heoglobin & hematocrit, etc). In a similar study, Long Evans rats were exposed to 400, 500, 600, or 700 MHz (CW or PW-1000 pulses per second, 3- or 30-usec pulse duration) MW at power densities up to 20 mW/cm2 and analyzed for lever pressing behavior. With exposure at 600 MHz (~resonant for the rat), work stoppage occured at above ~ 10 mW/cm2.
Findings		No Effects
Status		Completed With Publication
Principal Investigator		University of Utah, Salt Lake City, Utah - john.dandrea@navy.brooks.af.mil
Funding Agency		AF, USA
Country		UNITED STATES
References		D'Andrea, JA et al. Bioelectromagnetics, (1986) 7:45-56 D'Andrea, JA et al. Bioelectromagnetics, (1986) 7:315-328 D'Andrea,, JA et al. ELECTROMAGNETIC FIELDS AND NEUROBEHAVIORAL FUNCTION, Progress in Clinical and Biological Research, Volume 247, M.E. O'Connor and R.H. Lovely, editors. , (1988) 247:289-308 DeWitt, JR et al. Bioelectromagnetics, (1987) 8:149-157 DeWitt, JR et al. J. Microwave Power, (1982) 17:282-283 D'Andrea, JA et al. J. Microwave Power, (1980) 15:123-135 D'Andrea, JA et al. J. Microwave Power, (1979) 14:351-362 D'Andrea, JA et al. Radio Sci., (1977) 12:251-256 D'Andrea, JA et al. HIGH PEAK POWER MICROWAVE PULSES AT 1.3 GHz: EFFECTS ON FIXED INTERVAL AND REACTION TIME PERFORMANCE IN RATS, (1987) :- D'Andrea, JA et al. BEHAVIORAL EFFECTS OF HIGH PEAK POWER MICROWAVE PULSES: HEAD EXPOSURE AT 1.3 GHz, (1992) :- Hatcher, DJ et al. Report, (1992) :- D'Andrea, JA et al. BIOLOGICAL EFFECTS OF ELECTROMAGNETIC WAVES. U.S. Department of Health, Education and Welfare. , (1976) 1:257-273 D'Andrea, JA Bioelectromagnetics, (1999) 20 (suppl 4):64-74
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