ID Number		601
Study Type		In Vivo
Model		3 GHz (PW) exposure to pregnant mice and analysis of teratogenicity and development
Details		Kumming mice (pregnant dams) were exposed to 3 GHz RF (PW-937 pps, 1.2 usec pulse duration) at an SAR of 3-3.5 W/kg for 5 hr day from the first day of gestation throughout the pregnancy, and their offspring were irradiated from day 3 to day 20 after birth. At 22 days of age, the pups were sacrificed and brain & liver tissues analyzed by immunohistolochemistry. Exposure at this relatively high level resulted in a decrease in succinate dehydrogenase in the hypothalamus & liver as well as catecholamine and monoamine oxidase levels in the hypothalamus. While teratogenic effects were not observed, the authors suggest that microwave radiation at this level may inhibit mitochondrial electron transport chain function. Previous studies had reported effects on mitochondrial marker enzymes in mouse brains.
Findings		Effects
Status		Completed With Publication
Principal Investigator		Zhejiang University, Hangzhou, Zhejiang, China - hch@mail.hz.zj.cn
Funding Agency		CDC / NIEHS, China
Country		CHINA
References		Chiang, H et al. J. Bioelectricity, (1987) 6:197-204 Chiang, H et al. J. Bioelect., (1984) 3:361-366
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