ID Number		599
Study Type		In Vivo
Model		2450 MHz (CW, PW, AM-16 Hz) exposures to rats and analysis of brain signaling
Details		Rats were exposed acutely to either 2 GHz (CW & PW - 6000 pulses/second, 10 msec pulses), 2.8 GHz (PW - 500 pulses/sec, 10 msec pulses), or 500 MHz (PW – 16 Hz) at incident power densities of 0, 1, 5, 10, 20, or 50 mW/cm2 for 30 minutes in the far field (under these conditions, power densities greater than 10 mW/cm2 produced moderate (1-3 C) hyperthermia). Rats were also exposed chronically to 2450 MHz RF at 0, 1, or 2 W/kg for 23 hrs/day for 1 week in a circular waveguide (at 2 W/kg the rats were reported as appearing warm as they stretched out in the cages, but they did not appear to be in any distress). Following exposure, animals were killed and brain tissue was analyzed for synapsin I levels (by RIA) and synaptosomal phosphorylation. Only in animals acutely exposed at hyperthermic levels (50 mW/cm2) was synapsin I phosphorylation significantly depressed. No other effects were observed.
Findings		Effects (only at thermal levels)
Status		Completed With Publication
Principal Investigator		The Rockefeller Univiversity, USA
Funding Agency		Private/Instit.
Country		UNITED STATES
References		Browning, MD et al. Neurotoxicol. Teratol., (1988) 10:461-464
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