ID Number		471
Study Type		In Vitro
Model		147, 50 MHz (CW & AM-16 Hz) exposure to chick brain and analysis of Ca++ efflux
Details		Chick forebrain tissue was exposed to 147 MHz (CW or AM-16 Hz) RF for 20 minutes at power densities ranging from 0.1 to 2.7 mW/cm2 in a TEM cell. Exposure resulted in both positive and negative effects on efflux of Ca++ from brain tissue depending upon the modulation pattern and the power density of RF exposure. In addition, temperature had an effect on Ca++ efflux. The authors suggest “windows” of modulation and power density to produce these effects. In more recent studies, Blackman et al exposed chick brain tissue to 50 MHz (AM-16 Hz) for 20 minutes at SARs of between 0.36 – 5.4 W/kg. Ca++ efflux was observed at specific exposure “windows”. The authors speculate on mechanisms of both AM and SAR “windows” for Ca++ efflux, and suggest that low frequency modulations and ELF magnetic fields may be responsible.
Findings		Effects
Status		Completed With Publication
Principal Investigator		EPA, RTP North Carolina, USA - blackman.carl@epa.gov
Funding Agency		NCI, USA
Country		UNITED STATES
References		Blackman, CF et al. Bioelectromagnetics, (1989) 10:115-128 Joines, WT et al. Bioelectromagnetics, (1981) 2:411-413 Blackman, CF et al. Radio Sci., (1979) 14:93-98 Joines, WT et al. Bioelectromagnetics, (1980) 1:271-275 Blackman, CF et al. Bioelectromagnetics, (1980) 1:277-283 Blackman, CF et al. Bioelectromagnetics, (1980) 1:35-43
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