ID Number		415
Study Type		In Vitro
Model		2450 MHz (CW) exposure to CHO cells and analysis of cytogenic abnormalities (+/- co-mutagens) and growth
Details		CHO (Chinese hamster ovary) cells were exposed to 2450 MHz (CW) at an SAR of 33.8 W/kg for 2 hr at 37 C and analyzed for sister chromatid exchange frequency either with or without adriamycin treatment to determine whether RF could promote the effects of a known agent causing genotoxic effects and disrupting the cell cycle. Maximum temperature in the exposed samples was 39.7 degrees C. No effects of RF exposure were observed either without or in combination with MMC treatment. In a related study, CHO cells were exposed as above either with or without simultaneous exposure to mitomycin C at ~33.8 W/kg (incubation temperatures up to 39.2 degrees C) and analysed for sister chromatid exchanges. Again, no significant increase in SCE frequency was observed as a result of RF exposure either alone or in combination with MMC.
Findings		No Effects
Status		Completed With Publication
Principal Investigator		University of Texas, San Antonio TX, USA
Funding Agency		AF, USA
Country		UNITED STATES
References		Ciaravino, V et al. Bioelectromagnetics, (1991) 12:289-298 Ciaravino, V et al. Environ. Mutagen., (1987) 9:393-399
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