ID Number		347
Study Type		In Vitro
Model		1800 MHz (GSM) exposure to cell lines and analysis of the formation of functional neuronal nicotinic receptors
Details		SY5Y, DK-N-BE, IMR32 (neuroblastoma cell lines expressing ganglionic nAChRs), DAOY (medulloblastoma cell line expressing central nAChRs), and NT2 (teratocarcinoma cell line that differentiates into various phenotypes upon RA stimulation) will be exposed in culture to 1800 MHz (GSM) and analyzed for nicotinic subunits a3, a5, b4, b2, and a7 using Northern blot and RNase protection. Further, the expression of homeodomain-containing Phox2a and Phox2b (neuronal differentiation transcription factors) will be measured.
Findings		Ongoing
Status		Ongoing
Start Date
End Date
Principal Investigator		Univ. Milan, Milan, Italy - Clementi@csfic.mi.cnr.it
Funding Agency		EU, VERUM, Germany, REFLEX, EU 5th Framework, Europe
Country		ITALY
References
Comments