ID Number		343
Study Type		In Vitro
Model		900, 1800 MHz (CW, GSM), 2450 MHz exposure to human lymphocytes and analysis of growth
Details		Peripheral blood mononuclear cells (PBMC) from human donors (n=25) were exposed to 900 MHz (GSM, CW) for either 1 hr/day, 3 days at an SAR of 76 mW/kg (for GSM) or 3 hours (30 minutes on, 30 minutes off to avoid heating) immediately after seeding as well as at 24 hours and 48 hours at an SAR of 70 mW/kg (for CW). Exposure to the GSM signal resulted in a significant decrease in DNA synthesis and increase in apoptosis as compared to sham exposed cells. Exposure to the CW signal did not affect cell proliferation, apoptosis, or mitochondrial membrane potential. The temperature of the culture was reported not to increase above 0.3 degrees during exposure. The authors interpret the data as suggesting a non-thermal effect, but the human relevance of such a small effect was questionable.
Findings		Effects
Status		Completed With Publication
Principal Investigator		Univ. Bologna, Bologna, Italy - bersani@gpxbof.df.unibo.it
Funding Agency		EU, VERUM, Germany, REFLEX, EU 5th Framework, Europe
Country		ITALY
References		Capri , M et al. Radiation Research, (2004) 162:211-218 Capri , M et al. Int J Rad Biol , (2004) 80:389-397
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