ID Number		2681
Study Type		In Vivo
Model		The goal of this research was to study the dependence of brain dielectric properties at 1 GHz using experimental swine model of acute ischemic stroke.
Details		AUTHORS' Conclusions: Semenov et al. 2017 (IEEE #6652): This study has demonstrated that acute ischemic stroke causes immediate changes in dielectric properties of brain tissue and the degree of such changes de pends on the development of ischemic injury. The data also showed that, if blood supply to brain tissue is restored (before irreversible tissue damage occurs), immediate changes in dielectric properties occurred in the opposite trajectory to that of the occlusion event. It ha s been previously suggested that, dielectric properties of brain tissues from different species (human, primate, canine, ovine , and swine) behave very much alike electrically [Lin, 1975]. Therefore, some would expect similar behavior in dielectric properties of human brain tissue to ischemia, observed in this study using swine model. The knowledge of the dependence of dielectric properties of brain tissue in acute ischemic stroke is fundamental for applicability of EMT for stroke detection. Immediate response of brain tissue dielectric properties to occlusion/reperfusion is an important finding, as it provides an opportunity for EMT application in brain monitoring after the stroke and in an assessment of an efficacy of treatment. Further, EMT may represent a novel imaging modality for the assessment of treatment efficacy in the management of ischemic brain injuries.
Findings		Not Applicable to Bioeffects
Status		Completed With Publication
Principal Investigator		EMTensor GmbH,Vienna, Austria
Funding Agency		EMTensor GmbH, Vienna Austria.
Country		AUSTRIA
References		Semenov, S et al. Bioelectromagnetics., (2017) 38:158-163
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