ID Number		2552
Study Type		In Vivo
Model		Biochemical endpoints (thiobarbituric and reactive species (TBARS), reduced glutathione (GSH) content, catalase activity, glutathione reductase (GR) and glucose) were measured in rats exposed for 40 or 60 days to RF fields (900 and 1800 MHz).
Details		AUTHORS' ABSTRACT: Achudume et al. 2010 (IEEE #6288): To investigate the oxidative stress-inducing potential of non-thermal electromagnetic fields in rats. Male Wister rats were exposed to electrical field intensity of 2.3 ± 0.82 ¼V/m . Exposure was in three forms: continuous waves, or modulated at 900 MHz or modulated GSM-nonDTX. The radio frequency radiation (RFR) was 1800 MHz, specific absorption radiation (SAR) (0.95-3.9 W/kg) for 40 and/or 60 days continuously. Control animals were located > 300 m from base station, while sham control animals were located in a similar environmental conditions, but in the vicinity of a non-functional base station. The rats were assessed for thiobarbituric and reactive species (TBARS), reduced glutathione (GSH) content, catalase activity, glutathione reductase (GR) and glucose residue after 40 and 60 days of exposure. At 40 days, electromagnetic radiation failed to induce any significant alterations. However, at 60 days of exposure various attributes evaluated decreased. The respective decreases in both nicotinamide adenine dinucleotide phosphate (NADPH) and Ascorbate- linked lipid peroxidation (LPO) with concomitant diminution in enzymatic antioxidative defense systems resulted in decreased glucose residue. The present studies showed some biochemical changes that may be associated with a prolong exposure to electromagnetic fields and its relationship to the activity of antioxidant system in rat Regular assessment and early detection of antioxidative defense system among people working around the base stations are recommended.
Findings		Effects
Status		Completed With Publication
Principal Investigator		Obafemi Awolowo U, Ile-Ife, Nigeria
Funding Agency		?????
Country		NIGERIA
References		Achudume, A et al. J. Electromagnetic Analysis & Applications., (2010) 2:482-487
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