ID Number		2496
Study Type		In Vivo
Model		DNA damage was assessed using alkaline comet assay in the brain of rats exposed to microwaves for 30 days at three frequencies (900, 1800 and 2450 MHz).
Details		AUTHORS' ABSTRACT: Deshmukh et al. 2013 (IEEE #6023): Background: Non-ionizing radiofrequency radiation has been increasingly used in industry, commerce, medicine and especially in mobile phone technology and has become a matter of serious concern in present time. Objective: The present study was designed to investigate the possible deoxyribonucleic acid (DNA) damaging effects of low-level microwave radiation in brain of Fischer rats. Materials and Methods: Experiments were performed on male Fischer rats exposed to microwave radiation for 30 days at three different frequencies: 900, 1800 and 2450 MHz. Animals were divided into 4 groups: Group I (Sham exposed): Animals not exposed to microwave radiation but kept under same conditions as that of other groups, Group II: Animals exposed to microwave radiation at frequency 900 MHz at specific absorption rate (SAR) 5.953 × 104 W/kg, Group III: Animals exposed to 1800 MHz at SAR 5.835 × 104 W/kg and Group IV: Animals exposed to 2450 MHz at SAR 6.672 × 104 W/kg. At the end of the exposure period animals were sacrificed immediately and DNA damage in brain tissue was assessed using alkaline comet assay. Results: In the present study, we demonstrated DNA damaging effects of low level microwave radiation in brain. Conclusion: We concluded that low SAR microwave radiation exposure at these frequencies may induce DNA strand breaks in brain tissue.
Findings		Effects
Status		Completed With Publication
Principal Investigator		Univ College of Med Sciences and GTB Hospital, U o
Funding Agency		Indian Council of Med Res (ICMR)
Country		INDIA
References		Deshmukh, PS et al. Toxicol Int., (2013) 20:19-24
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