ID Number		2330
Study Type		In Vivo
Model		DNA damage, reactive oxygen species and other endpoints were assessed in quail embryos exposed in ovo to 900 and 1800 MHz.
Details		AUTHORS' ABSTRACT: Tsybulin et al. 2013 (IEEE #5360): Purpose: Our study was designed to assess the effects of low intensity radiation of a GSM (Global System for Mobile communication) 900 MHz cellular phone on early embryogenesis in dependence on the duration of exposure. Materials and methods: Embryos of Japanese Quails were exposed in ovo to GSM 900 MHz cellular phone radiation during initial 38 h of brooding or alternatively during 158 h (120 h before brooding plus initial 38 h of brooding) discontinuously with 48 sec ON (average power density 0.25 ¼W/cm2, specific absorption rate 3 ¼W/kg) followed by 12 sec OFF intervals. A number of differentiated somites were assessed microscopically. Possible DNA damage evoked by irradiation was assessed by an alkaline comet assay. Results: Exposure to radiation from a GSM 900 MHz cellular phone led to a significantly altered number of differentiated somites. In embryos irradiated during 38 h the number of differentiated somites increased (p < 0.001), while in embryos irradiated during 158 h this number decreased (p < 0.05). The lower duration of exposure led to a significant (p < 0.001) decrease in a level of DNA strand breaks in cells of 38-h embryos, while the higher duration of exposure resulted in a significant (p < 0.001) increase in DNA damage as compared to the control. Conclusion: Effects of GSM 900 MHz cellular phone radiation on early embryogenesis can be either stimulating or deleterious depending on the duration of exposure.
Findings		Effects
Status		Completed With Publication
Principal Investigator		Nat Acad of Sc of Ukraine, Kyiv, Ukraine
Funding Agency		?????
Country		UKRAINE
References		Tsybulin , O et al. International Journal of Radiation Biology., (2013) 89:756-763 Burlaka, A et al. The Ukrainian Biochemical Journal. , (2022) 94:95-104
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