ID Number		2310
Study Type		Epidemiology
Model		This paper describes a 1) case-control study on the association of mobile phone use and vestibular schwannomas and a 2) case-case study using MRI to study the location and volume of the tumors.
Details		AUTHORS' ABSTRACT: Moon et al. 2013 (IEEE #5314): Abstract Vestibular schwannomas (VSs) grow in the region where the energy from mobile phone use is absorbed. We examined the associations of VSs with mobile phone use. This study included 119 patients who had undergone surgical tumor removal. We used two approaches in this investigation. First, a casecontrol study for the association of mobile phone use and incidence of VSs was conducted. Both cases and controls were investigated with questions based on INTERPHONE guidelines. Amount of mobile phone use according to duration, daily amount, and cumulative hours were compared between two groups. We also conducted a casecase study. The location and volume of the tumors were investigated by MRI. Associations between the estimated amount of mobile phone use and tumor volume and between the laterality of phone use and tumor location were analyzed. In a casecontrol study, the odds ratio (OR) of tumor incidence according to mobile phone use was 0.956. In the casecase study, tumor volume and estimated cumulative hours showed a strong correlation (r2=0.144, p =0.002), and regular mobile phone users showed tumors of a markedly larger volume than those of non-regular users (p <0.001).When the analysis was limited to regular users who had serviceable hearing, laterality showed a strong correlation with tumor side (OR=4.5). We found that tumors may coincide with the more frequently used ear of mobile phones and tumor volume that showed strong correlation with amount of mobile phone use, thus there is a possibility that mobile phone use may affect tumor growth.
Findings		Effects
Status		Completed With Publication
Principal Investigator		Yonsei U College of Medicine, Seoul, South Korea
Funding Agency		Nat'l Res Prog, Korea
Country		KOREA, REPUBLIC OF
References		Moon, IS et al. Tumor Biology. , (2014) 35:581-587
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