ID Number		2227
Study Type		In Vivo
Model		Static magnetic field exposure to rats and analysis of oxidative stress levels in the frontal cortex and hippocampus of the brain.
Details		Rats were exposed to static magnetic fields at 128 milliT for 1 h/day for 30 days. The authors report exposure decreased levels of glutathione peroxidase, CuZn superoxide dismutase, and catalase in the frontal cortex and hippocampus. Glutathione levels, however, were not affected. There was also a significant increase in metallothionein level but not 8-oxo-7,8-dihydro-2'-deoxyguanosine (8-oxodGuo) in the frontal cortex, indicating the absence of DNA oxidation. The authors conclude that sub-chronic exposure induced oxidative stress in the rat hippocampus and frontal cortex, with increased metallothionein levels protecting against oxidative DNA damage.
Findings		Effects
Status		Completed With Publication
Principal Investigator		Aix-Marseille Université CNRS, France
Funding Agency		Private/Instit.
Country		FRANCE
References		Amara, S et al. Gen Physiol Biophys, (2009) 28:260-265 Amara, S et al. J Trace Elem Med Biol., (2006) 20:263-269 Amara, S et al. Toxicology and industrial health., (2011) 27:99-106 Amara, S et al. Physics in medicine and biology., (2007) 52:889-898
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