ID Number		2209
Study Type		In Vitro
Model		1800 MHz (GSM) exposure to T-cell, monocyte, and fibroblast cell lines and analysis of protein expression
Details		Jurkat human T-cell leukemia, human fibroblasts, activated (via phytohemagglutinin) and inactive primary human mononuclear cells were exposed to 1800 MHz GSM signals at 2 W/kg (5 minutes on, 5 minutes off) for 2, 4, and 8 hours - similar exposure conditions as used by Diem et al. and Schwarz et al reporting DNA breaks. The authors report no effect on protein expression from 2D gels at 2 and 4 hours of exposure, although 8 hour exposures increased the expression of 14 protein spots including hsp70, ubiquitin carboxyl-terminal hydrolase 14, and 26S protease regulatory subunit 6B. The expression change was greatest in human fibroblasts followed by Jurkat T-leukemia cells and only marginal in monocytic cells. The authors also report a temperature increase of less than 0.15 degrees and postulate an increased rate of protein turnover stemming from protein folding problems caused by RF interference with hydrogen bonds.
Findings		Effects
Status		Completed With Publication
Principal Investigator		Medical University Vienna, Austria
Funding Agency		Private/Instit.
Country		AUSTRIA
References		Gerner, C et al. Int Arch Occup Environ Health., (2010) 83:691-702
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