ID Number		2168
Study Type		Epidemiology
Model		Occupational and residential exposure to residents in France and correlation with brain tumors
Details		Cases of malignant primary brain tumors (n = 122) in southern France were evaluated for retrospective occupational and environmental exposures. Exposure information was collected via standard questionnaire and face-to-face interview. In addition to a significant risk for the use of glue (OR = 17.58, 95% CI 1.75 - 176.62) during leisure activities, there was an inverse correlation (protective effect) for living near mobile phone base stations (OR=0.49, 95% CI 0.26 - 0.92). AUTHORS' ABSTRACT: Coureau et al. 2014 (IEEE #5678): The carcinogenic effect of radiofrequency electromagnetic fields in humans remains controversial. However, it has been suggested that they could be involved in the aetiology of some types of brain tumours. Objectives The objective was to analyse the association between mobile phone exposure and primary central nervous system tumours (gliomas and meningiomas) in adults. Methods CERENAT is a multicenter case-control study carried out in four areas in France in 20042006. Data about mobile phone use were collected through a detailed questionnaire delivered in a face-to-face manner. Conditional logistic regression for matched sets was used to estimate adjusted ORs and 95% CIs. Results A total of 253 gliomas, 194 meningiomas and 892 matched controls selected from the local electoral rolls were analysed. No association with brain tumours was observed when comparing regular mobile phone users with non-users (OR=1.24; 95% CI 0.86 to 1.77 for gliomas, OR=0.90; 95% CI 0.61 to 1.34 for meningiomas). However, the positive association was statistically significant in the heaviest users when considering life-long cumulative duration (e896h, OR=2.89; 95% CI 1.41 to 5.93 for gliomas; OR=2.57; 95% CI 1.02 to 6.44 for meningiomas) and number of calls for gliomas (e18360 calls, OR=2.10, 95% CI 1.03 to 4.31). Risks were higher for gliomas, temporal tumours, occupational and urban mobile phone use. Conclusions These additional data support previous findings concerning a possible association between heavy mobile phone use and brain tumours.
Findings		No Effects
Status		Completed With Publication
Principal Investigator		Hôpital Timone Adultes, Marseille, France
Funding Agency		Private/Instit.
Country		FRANCE
References		Spinelli, V et al. Presse Med, (2010) 39:335-344 Baldi , I et al. Int J Cancer., (2011) :- Coureau, G et al. Occup Environ Med., (2014) 71:514-522 Coureau, G et al. Occup Environ Med., (2015) 72:79-80
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