ID Number		2140
Study Type		In Vivo
Model		50 Hz (ELF) exposure to rats and analysis of behavior
Details		Sprague Dawley rats (n = 32) were exposed to 50Hz ELF at 0.5 milliT for either 8 hr/day for 5 days or 24 hr/day for 4-6 weeks. The authors report longer term RF exposure decreased performance in a maze test (indicating anxiety) and decreased performance in a forced swim test (indicating depression, as seen by increased floating time). The authors report no effect of exposure on body or organ weights, although there was an increased blood glucose level in the long-term exposure group. The authors also observed increased proopiomelanocortin mRNA in the anterior lobe of the pituitary but no effect on serum ACTH or corticosterone levels. The authors interpret the findings as suggesting RF exposure acts as a mild stressors and could be a factor in developing depression. In a subsequent study, rats exposed as above for 20 minutes were reported to cause discomfort and anxiety and influence behavior.
Findings		Effects
Status		Completed With Publication
Principal Investigator		Eötvös Loránd University, Budapest, Hungary
Funding Agency		Private/Instit.
Country		HUNGARY
References		Balassa, T et al. Acta Physiol Hung, (2009) 96:437-448 (448 missing) Szemerszky, R et al. Brain Res Bull., (2010) 81:92-99
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