ID Number		2134
Study Type		In Vivo
Model		RF exposure (900, 1880-1900 MHz) of pregnant mice and rats and analysis of bone development and other developmental effects in offspring.
Details		Pregnant Balb/c mice were exposed to 900 MHz (GSM) from day 5 prior to mating through gestation for either 0, 6, or 30 minutes/day using a mobile phone source (presumable hooked up to the network) and mounted to the bottom of the cage. The authors report E-field strengths inside the cage of 30 +/- 5 V/m with a corresponding estimated SAR of 0.6 - 0.94 W/kg. After birth, pups (n = 63) were analyzed within 5 hours after birth for structural or morphological abnormalities. The authors report no obvious phenotypic abnormalities, although histochemical evaluation showed decreased ossification of cranial bones and thoracic ribs, as well as displacement of Meckelian cartilage. The effects were transient, and not observed in pups analyzed several weeks after exposure (n = 27). AUTHORS' ABSTRACT: Stasinopoulou et al. 2016 (IEEE #6444): In the present study, to evaluate the effects of wireless 1880-1900MHz Digital Enhanced Communication Telephony (DECT) base radiation on fetal and postnatal development, Wistar rats were exposed at an average electric field intensity of 3.7V/m, 12h/day, during pregnancy. After parturition, a group of dams and offspring were similarly exposed for another 22 days. Controls were sham-exposed. The data showed that DECT base radiation exposure caused heart rate increase in the embryos on the 17th day of pregnancy. Moreover, significant changes on the newborns' somatometric characteristics were noticed. Pyramidal cell loss and glia fibrilliary acidic protein (GFAP) over-expression were detected in the CA4 region of the hippocampus of the 22-day old pups that were irradiated either during prenatal life or both pre- and postnatally. Changes in the integrity of the brain in the 22-day old pups could potentially be related to developmental behavioral changes during the fetal period.
Findings		Effects
Status		Completed With Publication
Principal Investigator		University of Athens, Greece
Funding Agency		Private/Instit.
Country		GREECE
References		Fragopoulou, AF et al. Pathophysiol., (2010) 17:169-177 Stasinopoulou, M et al. Reprod Toxicol. , (2016) 65:248-262
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