ID Number		2070
Study Type		In Vitro
Model		925 MHz (CW) exposure to purified bacterial membrane channels and analysis of ion flow
Details		Purified OmpF porin channel protein from E.coli embedded in a lipid bilayer was exposed to 925 MHz (CW) and ion flow via voltage clamp was evaluated. The authors report increased channel gating and voltage sensitivity with exposure that lasted for several milliseconds after the field source was terminated. The authors also report that similar effects could be seen with small non-RF temperature increases, and did not know if the effects due to RF were thermal or non-thermal. They speculate that exposure affected both the dynamics and conformation of the channel protein, and the mechanism may involve interactions with key amino acid side-chain groups or indirectly via interactions with electrolytes or the lipid membrane.
Findings		Effects
Status		Completed With Publication
Principal Investigator		University of Tehran, Iran
Funding Agency		Private/Instit.
Country		IRAN (ISLAMIC REPUBLIC OF)
References		Mohammadzadeh, M et al. Eur Biophys J, (2009) 38:1069-1078 Ketabi, N et al. Electromagnetic biology and medicine., (2015) 34:1-13
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