ID Number		2051
Study Type		In Vitro
Model		50 Hz (ELF) exposure to human colon adenocarcinoma cells and analysis of reactive oxygen species, oxidative protein damage and subsequent protein degradation
Details		Human colon adenocarcinoma (Caco2) cells were exposed to 50 Hz (ELF) at 1 mT for 24-72 hrs and analyzed for viability, growth, reactive oxygen species, protein oxidation, and protein activity. Specifically, the authors report an activation of the 20S proteasome complex that was enhanced by co-exposure with TPA and blocked by co-exposure with the anti-oxidant EGCG, suggesting the effects of ELF exposure may have been mediated by an increase in intracellular free radicals.
Findings		Effects
Status		Completed With Publication
Principal Investigator		University of Camerino, Italy - annamaria.eleuteri@unicam.it
Funding Agency		Private/Instit.
Country		ITALY
References		Eleuteri, AM et al. J Biomed Biotechnol., (2009) Volume 2009 Article ID 834239:(10 pages)-
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