ID Number		1929
Study Type		In Vivo
Model		2450 MHz (CW) exposure to newborn and adult rats and analysis of neuron development and activity
Details		Rats (7 days and 24 months old) were exposed to 2450 MHz CW) for either 4 hrs/day for 2 days (short term) or 8 hrs/day for 3 days (long term) using a converted microwave oven system and a measured power density of 2.8 mW/cm2. Rats were freely moving during exposures. Two hours after exposure, rats were sacrificed and proliferating cells from the brain subventricular zone (active area of developing neurons that migrate along the rostral migratory stream) were analyzed. The authors report significant decreases in neuron proliferation, migration, and body weight along with significant increases in c-fos expression in newborn but not adult rats exposed to 2450 MHz. They also report that the changes were age and dose dependent, with 2 hrs of exposure during the first postnatal month at a power density 2.8 mW/cm2 causing immediate changes in proliferating cell number, c-fos expression, and NADPH activity.
Findings		Effects
Status		Completed With Publication
Principal Investigator		Slovak Acad Sci Tech Univ, Kosice Slovakia
Funding Agency		VEGA, APVV, Slovakia
Country		SLOVAKIA (Slovak Republic)
References		Orendacova, J et al. Histochemica., (2011) 113 :723-728 Orendacova, J et al. Cell Mol Neurobiol, (2009) 29:6-7
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