ID Number		1803
Study Type		In Vitro
Model		900 MHz (CW) exposure to primary neutrophils and analysis of cell mobility
Details		Primary human neutrophils from fresh blood were exposed to 900 MHz (CW) RF at a calculated field strength of 0.392 V/m (no SAR provided) and evaluated for migration speed toward a chemical chemo-attractant. The authors temperature controls showed no effect when cells were cultured from 22 to 35 degrees, and at 35 degrees motility increased with a peak of ~4 fold at 40 degrees, after which motility again decreased with an upper threshold of 43 degrees as the cells succomb to heat stress. The authors report RF exposure had similar effects at these same target culture temperatures, except that the magnitude of increased motility was ~50% higher than with heat alone. The authors also report migration direction was perpendicular to the gradient of chemotaxic agent with RF exposure, and in addition cell shrinking, expanding, and rolling occured.
Findings		Effects
Status		Completed With Publication
Principal Investigator		University of Colorado, USA
Funding Agency		Private/Instit.
Country		UNITED STATES
References		Grimes, GJ et al. Exp Cell Res, (1979) 79:325-344 Aly , AA et al. IEEE Trans Biomed Eng, (2008) 55:795-797
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