ID Number		1604
Study Type		In Vitro
Model		2450 MHz (CW and intermittent) exposure to cells and analysis of growth, survival, and cell cycle distribution.
Details		Cells were exposed to 2450 MHz (CW) RF for 2 hrs at SARs up to 200 W/kg. The authors report that at SARs from from 0.05 to 1500 W/kg, cellular growth rate, survival and cell cycle distribution were not affected. At 200 W/kg, cell growth rate was suppressed and cell survival decreased. To determine whether there was a difference between continuous vs. intermittent exposure, the authors used several intermittent protocols including 300 W/kg(peak), 900W/kg(peak), 1500 W/kg(peak), and 100 W/kg CW (all 100W/kg mean). They report no significant differences between these conditions. When cells were exposed to 50 W/kg for 2h, the temperature of the medium rose to 39.1 °C, 100 W/kg exposure increased the temperature to 41.0 °C and 200 W/kg exposure increased the temperature to 44.1 °C. The authors conclude that suppression of proliferation at higher SARs was due to thermal effects.
Findings		Effects (only at thermal levels)
Status		Completed With Publication
Principal Investigator		Hirosaki University, Japan - miyskosh@cc.hirosaki-u.ac.jp
Funding Agency		MIC, Japan
Country		JAPAN
References		Takashima, Y et al. Bioelectromagnetics, (2006) 27:392-400 Shiina, T et al. IEEE Int Sympo Electromag Compat., (2014) 13:166-169
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