ID Number		1534
Study Type		In Vivo
Model		900 MHz (CW) exposure to rats and analysis of neurobehavioral effects and associated blood brain barrier permeability.
Details		Wistar rats were exposed to 900 MHz (CW) RF for either 24 hours (acute) or 2x per week for 6  12 weeks (subchronic) using a head only exposure apparatus. Exposure assessment was not defined, other than mentioning that the transmitting antenna emitted 1 watt of power. Rats treated with Mn 24 hours prior to acute and subchronic exposures were reported to have slightly increased Mn levels in the brain (presumably indicating blood brain barrier permeability), although the increases were not statistically significant. The authors also performed neurobehavioral tests and examined visual evoked potentials in some of the animals immediately prior to sacrifice and tissue analysis, and reported subchronic exposure + Mn treatment led to changes in neurobehavioral parameters. A subsequent study again reported acute RF exposure in combination with Mn treatment elevated Mn levels in teh brain, and following chronic exposures chnages in behavioral endpoints were observed. Additional studies were performed using 50 Hz ELF.
Findings		Effects
Status		Completed With Publication
Principal Investigator		Czech Natl Inst Public Health, Prague, Czech Repub
Funding Agency		Czech Republic Grant Agency
Country		CZECH REPUBLIC
References		Vojtisek, M et al. Electromagn Biol Med, (2005) 24:355-357 Vojtisek, M et al. Rev Environ Health, (1999) 14:251-256 Vojtisek, M et al. Electromagnetic biology and medicine., (2009) 28:188-193
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