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EMF Study
(Database last updated on Mar 27, 2024)
ID Number |
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1474 |
Study Type |
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In Vitro |
Model |
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60 Hz (pulsed) exposure to bone cells and analysis of DNA synthesis and proliferation |
Details |
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Osteosarcoma cell lines (TE-85, MG-63) and normal human osteoblast cells from surgical bone specimens were exposed to pulsed 60 Hz (1.3 msec pulse width, repeated at 75 Hz) for different times and analyzed for effects on proliferation. The authors report stimulation of DNA synthesis with normal human osteoblasts responding more rapidly to pulsed ELF than established cell lines. Other studies reported similar effects of pulsed 60 Hz on increasing DNA synthesis in articular chondrocytes. The authors speculate the importantce of their findings with respect to stimulation of fracture healing. The authors also report corresponding changes in gene expression and proteoglycan synthesis. |
Findings |
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Effects |
Status |
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Completed With Publication |
Principal Investigator |
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Dipartimento di Morfologia ed Embriologia, Univers - dmm@dns.unife.it
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Funding Agency |
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Agency Tech, Energy, Environ, Italy
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Country |
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ITALY |
References |
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De Mattei, M et al. Bioelectromagnetics, (2005) 26:207-214
De Mattei, M et al. Osteoarthritis Cartilage, (2004) 12:793-800
De Mattei, M et al. Connective Tissue Research, (2003) 44:154-159
De Mattei, M et al. Connective Tissue Research, (2001) 42:269-279
De Mattei, M et al. Bioelectromagnetics, (1999) 20:177-182
Pezzetti, F et al. Calcif Tissue Int, (1999) 65:396-401
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