ID Number		1471
Study Type		In Vitro
Model		60 Hz exposure to B cells in culture and analysis of gene expression and protein activity
Details		B-lineage lymphoid cells were exposed to 50 Hz ELF and analyzed for gene expression patterns. The authors report stimulation of protein tyrosine kinases Lyn and Syk, resulting in tyrosine phosphorylation of multiple downstream substrates and activation of protein kinase C (PKC). Because the effect occurred in Syk-deficient but not in Lyn-deficient cells, the authors conclude that Lyn kinase is necessary for EMF-induced tyrosine phosphorylation.
Findings		Effects
Status		Completed With Publication
Principal Investigator		University of Minnesota, Minneapolis MN, USA.
Funding Agency		NIH, USA
Country		UNITED STATES
References		Uckun, FM et al. J. Biol. Chem., (1995) 270:27666-27670
Comments