ID Number		1427
Study Type		In Vitro
Model		2450 MHz (CW) exposure to cells (thermal levels) and correlation between survival and heating effects
Details		CHO cells as well as Serratia marcescens bacteria contained within small 5-cm glass micro-capillary tubes were exposed to 2450 MHz RF (CW) at field strengths of 0.2-0.5 W/cm2. Exposure was performed by sealing the tubes after cells were loaded and placing them parallel to the electric field in a watertight and temperature controlled waveguide. The inside of the capillary tubes were coated with a liquid crystal to detect color changes cause by heating that was reported to be accurate to 0.02 degrees C. Even with high circulating water flow, local temperature increases of 0.1-0.25 degrees C were detected. Local temperature increases increased as circulating water flow was reduced from 300 ml/s to 100 ml/s. Cell survival assay results following RF exposure based on the detected temperature increases were in good agreement with non-RF hyperthermia studies, suggesting the effects of RF exposure were thermal in nature.
Findings		Effects (only at thermal levels)
Status		Completed With Publication
Principal Investigator
Funding Agency		NIH, USA
Country		UNITED STATES
References		Robinson, AY et al. Bioelectromagnetics, (1982) 3:237-245 Robinson, JE et al. Radiation Research, (1981) 88:542-551 Cheung, AY et al. J Microw Power, (1977) 12:42-43
Comments