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Brain tumor patients (n = 285 glioma, 97 with meningioma, 34 with acoustic neuroma, 55 with parotid gland tumors + matched controls) from Korea were analyzed for possible correlations with mobile phone use. Cases from one of 9 different University hospitals within the Seoul and Kyunggi Provinces between February 2002 to December 31, 2004 as well as additional cases identified from the Korean Central Cancer Registry were considered in the analysis vs. matched control groups. Conditional logistic regression was used to calculate adjusted odds ratios (OR). In addition, earlier preliminarily reports indicated significant associations between parotid gland tumors and headache and dizziness (p<0.05) as well as glioma and face itching (p<0.05). The authors also report associations between glioma and gender (OR=0.422, p<0.05) and age (OR=0.964, p<0.05), between meningioma and gender (OR=2.597, p<0.05) and age (OR=1.140, p<0.05), and acoustic neuroma and smoking (OR=0.270, p<0.01). Results: For the entire group, there were no significant association for glioma with regular mobile phone use, type of mobile phone, lifetime years of use, monthly service fee, and other exposure indices. Analyses restricted to self-respondents showed similar results. However, increased trends were observed in the highest categories of lifetime years of use (OR = 2.61; 95% CI 0.97-7.01), cumulative hours plus ipsilateral use (OR = 1.79; 95% CI 0.65-4.89), and average daily number of calls (OR = 5.38; 95% CI 1.31-22.1). The risks for contralateral use were slightly decreased but not significantly different than those of ipsilateral use. Conclusion: Our results do not support the hypothesis that the use of mobile phone increases glioma risk in Korean adults, however, we found nonsignificantly increasd risks among ipsilateral users. These findings warrant further evaluation for glioma risks among long term ipsilateral users. |