ID Number		1347
Study Type		In Vivo
Model		2450 MHz exposure to rats and analysis of gene expression and protein activity in various tissues
Details		Rats were exposed to 2450 MHz (CW) RF at a power density of 1 mW/cm2 for 60 days and analyzed for poly ADPR polymerase activity in various tissues. The authors report increased activity of 20% in the liver and 35% in the testis, and a 53% and 20 % decrease in activity in the brain diencephalon and cortex, respectively. No change was observed in spleen and kidney. Changes in ADPR polymerase activity were accompanied by concomitant changes in NAD+ levels. The suggest the results may be important events in carcinogenesis and tumor promotion. In a related paper, rats were exposed to a 73.5 MHz signal amplitude modulated at 16 Hz at an SAR of 0.4 W/kg for various times up to 3 weeks. The authors report changes in the threshold and response rate to heat and other noxious stimuli that suggest an increase in the emotional component of the response.
Findings		Effects
Status		Completed With Publication
Principal Investigator		All India Institute of Medical Sciences, New Delhi
Funding Agency		Private/Instit.
Country		INDIA
References		Mathur, R Electromagn Biol Med, (2008) 27:266-276 Singh, N et al. Indian J. Physiol. Pharmacol., (1994) 38:181-184
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