ID Number		1340
Study Type		In Vitro
Model		2450 MHz (CW) exposure to liposomes and analysis of membrane permeability
Details		Unilamellar phosphatidylcholine liposomes were exposed to 2450 MHz (CW) at for 5-20 minutes at both non-thermal and thermal levels and analyzed for leakage of 5(6)- carboxyfluorescein (loaded into the liposomes). The highest final temperature was 37.6 +/- 0.5 degrees C, which the authors report as well above the phase transition temperature of the lipid membrane. The authors report exposure did not result in any increased permeability above that produced by thermal heating.
Findings		No Effects
Status		Completed With Publication
Principal Investigator		Chalmers Univ. Technology, Sweden - yngve@elmagn.chalmers.se
Funding Agency		Research Council, Sweden
Country		SWEDEN
References		Bergqvist, B et al. Biochim. Biophys. Acta, (1994) 1201:51-54 Saalman, E et al. Biochim. Biophys. Acta, (1991) 1064:124-130
Comments		The authors suggest their study refutes results reported by Saalman et al. - reporting an increased liposome permeability due to non-thermal microwave exposure