ID Number		1282
Study Type		In Vitro
Model		2 - 8.75 GHz exposure of plasmid DNA and analysis of ss and ds breaks
Details		Isolated plasmid DNA exposed to 2 to 8.75 GHz (CW) microwaves at nonthermal levels and analyzed by gel electrophoresis for ss or ds DNA breaks (unwinding). Microwave-induced damage was first observed, but then further studies showed this effect was depent upon the presence of small amounts of copper and that cuprous, but not cupric, ions were able to mimic the effects produced by microwaves on DNA. Studies were also performed looking at resonant absorption in large DNA molecules.
Findings		No Effects
Status		Completed With Publication
Principal Investigator		FDA, USA
Funding Agency		FDA, USA
Country		UNITED STATES
References		Sagripanti, JL et al. Radiat. Res., (1987) 110:219-231 Sagripanti, JL et al. Int. J. Radiat. Biol., (1986) 50:47-50 Davis, CC et al. Bioelectrochem. Bioenerg., (1986) 16:76-81 Edwards, GS et al. Biophys. J., (1985) 47:799-807 Edwards, GS et al. Phys. Rev. Lett., (1984) 53:1284-1287 Swicord, ML et al. Biopolymers , (1983) 22:2513-2516 Swicord, ML et al. Biopolymers, (1982) 21:2453-2460 Davis, CC , (1987) :- Davis, CC , (1989) :-
Comments