ID Number		1108
Study Type		In Vitro
Model		836.55 MHz (TDMA) exposure to cultured cells and analysis of enzyme activity
Details		In initial in vitro studies, C3H 10T1/2 cells were exposed to an 835 MHz TDMA signal at 0.78, and 7.8 uW/g for up to 4 hours in a TEM cell with a 20 minute on / 20 minute off repeating cycle. Exposures followed induction of growth activity by a change of media (from serum free conditions). Initially, at the highest SAR level ODC activity was inhibited 50% after 3 and 4 hours (opposite the results reported by Penafiel et al., 1997, Bioelectro-magnetics 18:132-141 where murine L929 fibroblasts showed a 50% increase in ODC activity following an 8 hour exposure at a relatively high SAR - 2.5 W/kg). However, the Penafel et al studies were not looking at exposure following ODC induction by change of media. Importantly, in the present study the sham control C3H 10T1/2 cells in the high SAR study did not respond to serum induction as in the low SAR study or in reported sham-sham experiments in the paper. Also, similar studies using C6 glioma cells did not show any effect on ODC activity as compared to sham controls.
Findings		Effects
Status		Completed Without Publication
Principal Investigator		University of California at Riverside, USA
Funding Agency		Motorola
Country		UNITED STATES
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