ID Number		1052
Study Type		In Vivo
Model		1.4 GHz (PDC) exposure to rats and analysis of sleep, melatonin, estrogen, and immune function
Details		Sprague-Dawley rats (n=64 per group, 208 total) were exposed to 1439 MHz TDMA RF (50-Hz, 6.7 millisecond pulses comparable to Japanese PDC for mobile phones) for an average brain SAR of 7.5 W/kg, and the average whole body SARs of 1.9 and 2.0 W/kg for male and female rats, respectively. A total of 208 male and female rats were investigated. After acclimatization to a 12 h light-dark (LD) cycle, serum and pineal melatonin levels together with pineal serotonin level under a dark condition (less than 1 lux) were examined by radioimmunoassay. No significant differences in melatonin and serotonin levels were observed between the exposure, sham, and cage control groups. These results suggest that short term exposure to a 1439 MHz TDMA EMF, which is about four times stronger than that emitted by mobile phones, does not alter melatonin and serotonin synthesis in rats. In a related study ovariectomized female Sprague-Dawley rats (n = 32) were exposed to 1.4 MHz (PDC) RF field 4 hr for 3 consecutive days at a brain avg SAR of 7.5 W/kg. The authors report exposure did not affect uterine wet weight or serum estradiol levels.
Findings		No Effects
Status		Completed With Publication
Principal Investigator		Tokyo University, Japan - nagawa-1su@h.u-tokyo.ac.jp
Funding Agency		MIC, Japan
Country		JAPAN
References		Hata , K et al. Bioelectromagnetics, (2005) 26:49-53 Yamashita , H et al. Bioelectromagnetics., (2010) 31:573-575
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