ID Number		1011
Study Type		In Vivo
Model		1.28, 2.45, 5.62 GHz (CW) exposure to rodents and monkeys and analysis of thresholds for behavior disruption
Details		Rats were exposed to 1.28 and 5.62 GHz (CW) daily during an operant behavior task (a two-lever task - depression of one lever produced one of two different tones and the other lever produced food when depressed in the presence of the appropriate tone). Response rates were affected at a threshold of 4.94 W/kg for 1.28 GHz and 3.75 W/kg for 5.62 GHz exposures. The authors concluded that the rat's behavior was disrupted at a lower SAR at 1.28 than at 5.62 GHz because of deeper penetration of energy at the lower frequency, and because of frequency-dependent differences in anatomic distribution of the absorbed microwave energy. Other studies suggested MW exposure could be a reinforcing element during exposure of animals to cold environment. In studies done in food-deprived rhesus monkeys exposed to 225 MHz (CW) or 1.3 or 5.8 GHz (CW) during an operant behavior task, the behavior impairment threshold at 225 MHz was 8.1 mW/cm2; at 1.3 GHz it was 57 mW/cm2, and at 5.8 GHz it was 140 mW/cm2. These power densities were all associated with increases in colonic temperatures above sham-exposure levels, typically in the range of 1°C. Response-rate changes were not observed in the absence of concomitant temperature increases.
Findings		Effects (only at thermal levels)
Status		Completed With Publication
Principal Investigator		Naval Aerospace Medical Research Laboratory, Pensa
Funding Agency		Navy, USA
Country		UNITED STATES
References		Lu, S et al. ADVANCES IN ELECTROMAGNETIC FIELDS IN LIVING SYSTEMS [BOOK], J.C. Lin (Ed.), (2000) :207-264 de Lorge, JO Bioelectromagnetics, (1984) 5:233-246 de Lorge, JO et al. Bioelectromagnetics, (1980) 1:183-198 Sanza, JN et al. Radio Sci., (1977) 12:273-277 de Lorge, JO Radio Sci., (1979) 14:217-225 de Lorge, JO BIOLOGICAL EFFECTS OF ELECTROMAGNETIC WAVES. U.S. Department of Health, Education and Welfare., (1976) 1:158-174 Knepton, J et al. Naval Aerospace Medical Research Laboratory (NAMRL) Report #1291., (1983) :- Knepton, J et al. Naval Aerospace Medical Research Laboratory (NAMRL) Report #1293., (1983) :1-29 D'Andrea, JA et al. BIOLOGICAL EFFECTS AND MEDICAL APPLICATIONS OF ELECTROMAGNETIC ENERGY, (1990) :319-338 de Lorge, JO MICROWAVES AND THERMOREGULATION, (1983) :379-399 Marr, MJ et al. Electromagnetic Fields and Neurobehavioral Function, Progress in Clinical and Biological Research, Volume 247, M.E. O'Connor and R.H. Lovely, editors. , (1988) 247:219-234 de Lorge, JO Naval Aerospace Medical Research Laboratory (NAMRL) Report 1222. , (1976) :1-17 de Lorge, JO Naval Aerospace Medical Research Laboratory (NAMRL) Report #1289., (1983) :1-19
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